Synthesis of Poly(1,4-phenylene sulfide) from Diphenyl.
Diphenyl disulfide Phenyl disulfide 1,2-Diphenyldisulfane (not recommended) Identifiers; CAS Number. 882-33-7.
Flavouring ingredient Diphenyl disulfide is the chemical compound with the formula (C6H5S)2. This colorless crystalline material is often abbreviated Ph2S2. It is one of the most popular organic disulfides used in organic synthesis. Minor contamination by thiophenol is responsible for the disagreeable odour associated with this compound.
Typical experimental procedure: Diphenyl disulfide (109 mg, 0.5 mmol), PdCl 2 (dppf) (37 mg, 0.05 mmol), and zinc (80 mg, 1.2 mmol), were placed in a round-bottom flask containing a stirring bar, and a THF solution (5 mL) of the aryl bromide (1.0 mmol) was then added to the flask, and the resulting mixture was heated at reflux for 24 h.
We conducted our initial study with benzenediazonium tetrafluoroborate (1a) and CS 2 (2) as model substrates to examine the feasibility of the formation of diphenyl disulfide (3a) ().Various solvents were screened and to our delight, it was found that the reaction of 1a and 2 in DMF and DMSO gave the desired product in a moderate yield of 54% and 53%, respectively (Table 1, entries 7 and 8).
Scheme 2: Aryl sulfide synthesis. sulfur source, diphenyl disulfide was obtained as a major side product, which in turn hindered the arylation process and resulted in several other oxidized products of thiophenol. So, the readily available diphenyl disulfide was added as the thio-lating agent. Addition of excess disulfide (e.g., 5 equivalents) resulted in the formation of thiophenol as a major.
So, the readily available diphenyl disulfide was added as the thiolating agent. Addition of excess disulfide (e.g., 5 equivalents) resulted in the formation of thiophenol as a major side product along with other oxidized sulfur species. The amount of disulfide was varied from 0.5 equivalents to five equivalents; 1.7 equivalents of disulfide gave the best result. The photocatalytic reaction was.
Diphenyl disulfide. In a 100-mL, round-bottomed flask equipped with a magnetic stirrer are placed 11.0 g (10.25 ml, 0.1 mol) of benzenethiol and 50 mL of trifluoroethanol (Note 1). The mixture is stirred and cooled in an ice bath (Note 2) and 12.5 mL (3.73 g, 0.11 mol) of 30% aqueous hydrogen peroxide (Note 3) is added dropwise over a period of 15 min through an addition funnel. After.